National Heart Lung and Blood Institute

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About the National Heart Lung and Blood Institute Datasets

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The National Heart, Lung, and Blood Institute (or NHLBI) is a division of the National Institutes of Health, located in Bethesda, Maryland. It is tasked with allocating about $2.7 billion in United States tax revenue per year (fiscal year 2004 estimate), to advancing the understanding of: development and progression of disease, diagnosis of disease, treatment of disease, disease prevention, reduction of health care disparities within the American population, and advancing the effectiveness of the U.S. medical system.

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Other Datasets

The NHLBI posts links to other epidemiological studies on its website which can be located here:


The current directory listing (as of September, 2009):

Epidemiology Studies

Study Name

  • A Case-Control Etiologic Study of Sarcoidosis (ACCESS)
  • Atherosclerosis Risk in Communities Study (ARIC)
  • Bogalusa Heart Study (BHS)
  • Cardiovascular Health Study (CHS)
  • Coronary Artery Risk Development in Young Adults (CARDIA)
  • Cord Blood Transplant Study (COBLT)
  • Framingham Heart Study-Cohort
  • Framingham Heart Study-Offspring
  • Honolulu Heart Program (HHP)
  • Lipid Research Clinics- Prevalence Study (LRCPS)
  • NHLBI Growth and Health Study (NGHS)
  • National Longitudinal Mortality Study (NLMS)
  • Puerto Rico Heart Health Program (PRHHP)
  • Cooperative Study of Sickle Cell Disease (CSSCD)
  • Patient Registry for Primary Pulmonary Hypertension (PPH Registry)
  • Women's Ischemia Syndrome Evaluation (WISE)
  • Women's Health Initiative Observational Study (WHI-OS)
  • Alpha1,-Antitrypsin Deficiency Registry
  • Retrovirus Epidemiology Donor Study HTLV Cohort (REDS)
  • Multi-Ethnic Study of Athersclerosis (MESA)
  • Hemochromatosis and Iron Overload Screening Study (HEIRS)

Clinical Trials

Study Name

  • Acute Respiratory Distress Syndrome Clinical Network (ARDSNet 01/03): Lower versus higher tidal volume, lisofylline treatment and ketoconazole treatment (3 study factorial)
  • Acute Respiratory Distress Syndrome Clinical Network (ARDSNet 04): Assessment of low tidal volume and elevated end-expiratory pressure to obviate lung injury (ALVEOLI).
  • Acute Respiratory Distress Syndrome Clinical Network (ARDSNet02): Efficacy of Corticosteroids as Rescue Therapy for the Late Phase of Acute Respiratory Distress Syndrome (LaSRS)
  • Acute Respiratory Distress Syndrome Clinical Network (ARDSNet05): Fluid and Catheter Treatment Trial (FACTT)
  • Antiarrhythmics Versus Implantable Defibrillators(AVID)
  • Asymptomatic Cardiac Ischemia Pilot (ACIP)
  • Asthma Clinical Research Network: Beta Agonist in Mild Asthma (ACRN: BAGS)
  • Cardiac Arrhythmia Suppression Trial (CAST)
  • Asthma Clinical Research Network: Colchicine in Moderate Asthma (ACRN: CIMA)
  • Digitalis Investigation Group (DIG)
  • Intermittent Positive Pressure Breathing (IPPB)
  • Lipids Research Clinics Coronary Primary Prevention Trial (LRC-CPPT)
  • Post Coronary Artery Bypass Graft Study (CABG)
  • Activity Counseling Trial (ACT)
  • Aspirin Myocardial Infarction Study (AMIS)
  • Atrial Fibrillation Follow-up Investigation of Rhythm Management(AFFIRM)
  • Beta-Blocker Evaluation of Survival Trial (BEST)
  • Beta-Blocker Heart Attack Trial (BHAT)
  • Coronary Artery Surgery Study (CASS)
  • Dietary Approaches to Stop Hypertension - Sodium Study (DASH-Sodium)
  • Dietary Intervention Study in Children (DISC)
  • High Frequency Ventilation in Premature Infants Study (HIFI)
  • Hypertension Detection and Follow-up Program (HDFP)
  • Lung Health Study (LHS)
  • Magnesium in Coronaries Study (MAGIC)
  • Multiple Risk Factor Intervention Trial (MRFIT)
  • National Emphysema Treatment Trial (NETT)
  • Prospective Investigation of Pulmonary Embolism Diagnosis (PIOPED)
  • Psychophysiological Investigation of Myocardial Ischemia (PIMI)
  • Rapid Early Action for Coronary Treatment Study (REACT)
  • Raynaud's Treatment Study (RTS)
  • Asthma Clinical Research Network: The Salmeterol or Corticosteroids (ACRN: SOCS) and the *Salmeterol with and without Inhaled Corticosteriods (ACRN: SLIC) Trials
  • Studies of Left Ventricular Dysfunction (SOLVD)
  • Systolic Hypertension in the Elderly Program (SHEP)
  • T-Cell Depletion in Unrelated Donor Marrow Study (TCD)
  • Thrombolysis in Myocardial Infarction Study (TIMI II)
  • Thrombolysis in Myocardial Infarction Trial 3 (TIMI 3)
  • Women's Angiographic Vitamin and Estrogen Trial (WAVE)
  • Women's Health Initiative: Clinical Trials (WHI-CT)
  • Trials of Hypertension Prevention, Phases I and II
  • Asthma Clinical Research Network: Dose of Inhaled Corticosteroids with Equisystemic Effects (ACRN:DICE)
  • Asthma Clinical Research Network: Measuring Inhaled Corticosteroid Efficacy (ACRN:MICE)
  • Public Access Defibrillation (PAD) Community Trial
  • Bypass Angioplasty Revascularization Investigation (BARI)
  • Prevention of Events with Angiotensin Converting Enzyme Inhibition (PEACE) Trial
  • Viral Activation Transfusion Study (VATS)
  • Childhood Asthma Management Program (CAMP)
  • Trial to Reduce Alloimmunization to Platelets Study (TRAP)
  • Asthma Clinical Research Network: Beta Adrenergic Response by Genotype (ACRN-BARGE)
  • Lifestyle Interventions for Blood Pressure Control (PREMIER)
  • Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness (ESCAPE) Trial