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About rfam


Rfam is a large collection of multiple sequence alignments and covariance models covering many common non-coding RNA families. For each family in Rfam you can:

  • View and download multiple sequence alignments
  • Read family annotation
  • Examine species distribution of family members
  • Follow links to otherdatabases
  • In conjunction with the INFERNAL software suite, Rfam can be used to annotate sequences (including complete genomes) for homologues to known non-coding RNAs. Please read important information about using Rfam for genome annotation. We provide pre-calculated lists of putative RNAs in over 400 complete genomes, and a web search facility for short sequences.

Rfam makes use of a large amount of available data, especially published multiple sequence alignments, and repackages these data in a single searchable and sustainable resource. We have made every effort to credit individual sources on family pages, and have compiled a list of links to these sources here. If you find any of the data presented here useful, please also be sure to credit the primary source.

Access the Data

The most current website is now hosted by the Sanger institute: http://rfam.sanger.ac.uk/

The old website: http://www.sanger.ac.uk/Software/Rfam/

Contents of the Data

The following families of genomes (visit website to get more specific details):

  • Eukaryota
  • Bacteria
  • Archaea

miRBase::Sequences Also accessible from: http://microrna.sanger.ac.uk/sequences/index.shtml